1,612 research outputs found

    Water facilities in retrospect and prospect: An illuminating tool for vehicle design

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    Water facilities play a fundamental role in the design of air, ground, and marine vehicles by providing a qualitative, and sometimes quantitative, description of complex flow phenomena. Water tunnels, channels, and tow tanks used as flow-diagnostic tools have experienced a renaissance in recent years in response to the increased complexity of designs suitable for advanced technology vehicles. These vehicles are frequently characterized by large regions of steady and unsteady three-dimensional flow separation and ensuing vortical flows. The visualization and interpretation of the complicated fluid motions about isolated vehicle components and complete configurations in a time and cost effective manner in hydrodynamic test facilities is a key element in the development of flow control concepts, and, hence, improved vehicle designs. A historical perspective of the role of water facilities in the vehicle design process is presented. The application of water facilities to specific aerodynamic and hydrodynamic flow problems is discussed, and the strengths and limitations of these important experimental tools are emphasized

    The Second Virial Coefficient of Spin-1/2 Interacting Anyon System

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    Evaluating the propagator by the usual time-sliced manner, we use it to compute the second virial coefficient of an anyon gas interacting through the repulsive potential of the form g/r2(g>0)g/r^2 (g > 0). All the cusps for the unpolarized spin-1/2 as well as spinless cases disappear in the ω→0\omega \to 0 limit, where ω\omega is a frequency of harmonic oscillator which is introduced as a regularization method. As gg approaches to zero, the result reduces to the noninteracting hard-core limit.Comment: 9 pages, 2 figs include

    Akt and SGK protein kinases are required for efficient feeding by macropinocytosis

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    Macropinocytosis is an actin-driven process of large-scale and non-specific fluid uptake used for feeding by some cancer cells and the macropinocytosis model organism Dictyostelium discoideum. In Dictyostelium, macropinocytic cups are organized by ‘macropinocytic patches’ in the plasma membrane. These contain activated Ras, Rac and phospholipid PIP3, and direct actin polymerization to their periphery. We show that a Dictyostelium Akt (PkbA) and an SGK (PkbR1) protein kinase act downstream of PIP3 and, together, are nearly essential for fluid uptake. This pathway enables the formation of larger macropinocytic patches and macropinosomes, thereby dramatically increasing fluid uptake. Through phosphoproteomics, we identify a RhoGAP, GacG, as a PkbA and PkbR1 target, and show that it is required for efficient macropinocytosis and expansion of macropinocytic patches. The function of Akt and SGK in cell feeding through control of macropinosome size has implications for cancer cell biology.<br/

    Properties of the Interstitial in the Diamond-Type Lattice

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    Linear combination of atomic orbital—molecular orbital cluster calculations using extended Hückel theory suggest that the interstitial carbon atom in diamond prefers an interstitialcy configuration. The predicted minimum-energy configuration changes with charge state, providing a possible example of the Bourgoin mechanism for athermal migration of the interstitial in the presence of ionizing radiation
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